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by Skippack Pharmacy
GLP-1 medications, such as Semaglutide (Ozempic, Wegovy) and Tirzepatide (Mounjaro, Zepbound ), have shown great promise in assisting with weight management and blood sugar control. However, it is essential to understand how supplements can interact with these medications. Certain over-the-counter products marketed for weight loss may do more harm than good—and in some cases, they may be dangerous. Below, we’ve outlined supplements to avoid when using GLP-1 medications.
1. Garcinia Cambogia
Garcinia Cambogia, a supplement derived from a tropical fruit, is frequently promoted for its potential to suppress appetite and prevent fat formation. However, its actual impact on weight loss is minimal. The FDA advises against its use due to reports of severe side effects, including an elevated risk of liver failure. Combining Garcinia Cambogia with GLP-1 medications may increase liver strain, making this supplement especially dangerous.
2. Ephedra/Ephedra Alkaloids
Ephedra and its alkaloids were once popular for promoting thermogenesis (increased calorie burning) and appetite suppression. However, these substances are now prohibited by the FDA because of their potential to cause severe side effects, including heart attacks, strokes, and seizures. Using Ephedra alongside GLP-1 medications may heighten cardiovascular risks, making this combination unsafe.
3. Bitter Orange Extract
Bitter orange extract is another supplement marketed for weight loss, with claims that it boosts metabolism and suppresses appetite. However, evidence supporting its efficacy is limited, and it may lead to an undesirable increase in blood pressure. GLP-1 medications can already affect gastrointestinal motility, so adding bitter orange extract could lead to side effects like nausea or increase cardiovascular risks.
The Bottom Line
When using GLP-1 medications, it’s essential to focus on safe and evidence-based strategies for weight management. Supplements like garcinia cambogia, ephedra, and bitter orange extract can introduce unnecessary risks and interfere with your medication’s effectiveness. Before starting any supplement, always consult your healthcare provider or your trusted Skippack Pharmacy pharmacist to ensure it’s safe for you.
We’re Here to Help!
At Skippack Pharmacy, your health is our priority. If you have questions about GLP-1 medications or need guidance on weight management, don’t hesitate to reach out. We’re happy to provide personalized advice to help you achieve your goals safely and effectively.