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by Skippack Pharmacy
In recent years, GLP-1 medications have gained extreme popularity as a treatment option for weight loss. However, like all medications, these drugs come with potential side effects that users should be aware of before starting treatment. While they can be highly effective for weight loss, it is important to understand how these medications work and the possible side effects they may cause to ensure you make an informed decision when considering GLP-1 medications for weight loss.
Why Do These Medications Cause Side Effects?
Weight loss drugs like Wegovy and Zepbound work by activating a hormone known as GLP-1. This hormone helps you lose weight by slowing down digestion, which causes you to feel full for longer. However, this mechanism can also lead to nausea, indigestion, constipation, and diarrhea. Managing these side effects may seem confusing, but implementing lifestyle changes can help lessen their impact.
Common Side Effects & How to Manage Them
Nausea
Studies show that GLP-1 medications can trigger the “vomiting center” of the brain, which may contribute to nausea. Here’s what you can do:
- Do’s: Eat slowly during meals Eat bland, low-fat foods Eat foods with high water content, like Jell-O or soup Drink ginger or peppermint tea Inject the medication in the evening
- Don’ts: Lie down immediately after eating Eat overly spicy, greasy, or sugary foods
Indigestion
Because GLP-1 medications slow digestion, food may sit in the stomach longer, causing discomfort.
- Do’s: Eat smaller meals Drink plenty of water Keep your head elevated while sleeping
- Don’ts: Use straws (can introduce excess air into the stomach) Lie down immediately after eating Eat overly spicy, greasy, or sugary foods
Constipation
Clinical trials have found that 23.4% of participants experienced constipation while on semaglutide.
- Do’s: Engage in light exercise, like walking Eat plenty of fiber (whole grains, fruits, vegetables, beans) but increase intake gradually Stay hydrated
- Don’ts: Eat too close to bedtime **If these tips don’t help, you can try an over-the-counter stool softener like docusate.**
Diarrhea
Untreated diarrhea can lead to dehydration, so managing this side effect is crucial.
- Do’s: Take a probiotic Eat slowly during meals
- Don’ts: Drink sports drinks like Gatorade (which can worsen symptoms due to high sugar content)
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- **If diarrhea persists, an over-the-counter antidiarrheal like loperamide may help.**
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Injection
Site Pain Since GLP-1 medications are injections, some discomfort at the injection site is common.
- Do’s: Rotate injection sites between the abdomen and upper thigh Clean the area thoroughly before injection
- Don’ts: Wear tight clothing around the injection site
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- **If pain persists, consider taking an over-the-counter pain reliever like acetaminophen.**
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When to Contact Your Doctor or Pharmacist
While these side effects are common, they should not be debilitating. If any side effect persists or becomes severe, contact your physician or pharmacist for further guidance. Your healthcare provider can help adjust your treatment plan or provide additional solutions tailored to your needs. By understanding and proactively managing these side effects, you can maximize the benefits of GLP-1 medications while minimizing discomfort. If you have any concerns, don’t hesitate to seek professional advice!
Resources:
https://pmc.ncbi.nlm.nih.gov/articles/PMC9821052/https://www.blogs.joinmochi.com/blogs/can-ozempic-cause-constipationhttps://www.blogs.joinmochi.com/blogs/does-wegovy-cause-nausea-navigating-side-effects-and-treatmentshttps://www.blogs.joinmochi.com/blogs/why-does-wegovy-cause-diarrhea-insights-and-advice